The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1

Nuclear export of messenger RNA (mRNA) occurs by translocation of mRNA/protein complexes (mRNPs) through nuclear pore complexes (NPCs). The DEAD-box protein Dbp5 mediates export by triggering removal of mRNP proteins in a spatially controlled manner. This requires Dbp5 interaction with Nup159 in NPC...

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Detalhes bibliográficos
Main Authors: Hodge, Christine A., Tran, Elizabeth J., Noble, Kristen N., Alcazar-Roman, Abel R., Ben-Yishay, Rakefet, Scarcelli, John J., Folkmann, Andrew W., Shav-Tal, Yaron, Wente, Susan R., Cole, Charles N.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093121/
https://ncbi.nlm.nih.gov/pubmed/21576265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2041611
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