The potent calcitonin gene-related peptide receptor antagonist, telcagepant, does not affect nitroglycerin-induced vasodilation in healthy men

AIMS: To assess the effect of the calcitonin gene-related peptide (CGRP) receptor antagonist, telcagepant, on the haemodynamic response to sublingual nitroglycerin (NTG). METHODS: Twenty-two healthy male volunteers participated in a randomized, placebo-controlled, double-blind, two-period, crossover...

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Autores principales: Van der Schueren, Bart J, Blanchard, Rebecca, Murphy, M Gail, Palcza, John, De Lepeleire, Inge, Van Hecken, Anne, Depré, Marleen, de Hoon, Jan N
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2011
Materias:
Pharmacodynamics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093076/
https://ncbi.nlm.nih.gov/pubmed/21480950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03869.x
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