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Pathological accumulation of atrophin-1 in dentatorubralpallidoluysian atrophy

Dentatorubral-pallidoluysian atrophy (DRPLA) is caused by the expansion of polyglutamine (polyQ) in atrophin-1 (ATN1), also known as DRPLA protein. ATN1 is ubiquitously expressed in the central nervous system (CNS), although selective regions of CNS are degenerated in DRPLA, and this selective neuro...

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Hlavní autoři: Suzuki, Yasuyo, Yazawa, Ikuru
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093063/
https://ncbi.nlm.nih.gov/pubmed/21577324
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