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Copy Number Variants in pharmacogenetic genes

Variation in drug efficacy and toxicity remains an important clinical concern. Presently, single nucleotide polymorphisms (SNP) only explain a portion of this problem, even in situations where the pharmacological trait is clearly heritable. The Human CNV Project identified copy number variations (CN...

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Autors principals: He, Yijing, Hoskins, Janelle M., McLeod, Howard L.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092840/
https://ncbi.nlm.nih.gov/pubmed/21388883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2011.01.007
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