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Strand Invasion of Mixed-Sequence, Double Helical B-DNA by γPNAs Containing G-Clamp Nucleobases under Physiological Conditions
Peptide nucleic acids (PNAs) are the only class of nucleic acid mimics developed to date that has been shown to be capable of invading double helical B-form DNA. Recently, we showed that sequence limitation associated with PNA recognition can be relaxed by utilizing conformationally-preorganized γ-p...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092786/ https://ncbi.nlm.nih.gov/pubmed/21476606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2002554 |
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