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Monoclonal antibodies in neuro-oncology: Getting past the blood-brain barrier

Monoclonal antibodies (mAbs) are used with increasing success against many tumors, but for brain tumors the blood-brain barrier (BBB) is a special concern. The BBB prevents antibody entry to the normal brain; however, its role in brain tumor therapy is more complex. The BBB is closest to normal at m...

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Detalhes bibliográficos
Autor principal: Lampson, Lois A
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092616/
https://ncbi.nlm.nih.gov/pubmed/21150307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.2.14239
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