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TROY (TNFRSF19) is Overexpressed in Advanced Glial Tumors and Promotes Glioblastoma Cell Invasion via Pyk2-Rac1 Signaling

A critical problem in the treatment of malignant gliomas is the extensive infiltration of individual tumor cells into adjacent brain tissues. This invasive phenotype severely limits all current therapies, and to date, no treatment is available to control the spread of this disease. Members of the tu...

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Autori principali: Paulino, Vincent M., Yang, Zhongbo, Kloss, Jean, Ennis, Matthew J., Armstrong, Brock A., Loftus, Joseph C., Tran, Nhan L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092528/
https://ncbi.nlm.nih.gov/pubmed/20881009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0334
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