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Novel Signaling Complex Between TROY and EGFR Mediates Glioblastoma Cell Invasion

Glioblastoma is the most frequent primary brain tumor in adults and a highly lethal malignancy with a median survival of about 15 months. The aggressive invasion of the surrounding normal brain makes complete surgical resection impossible, increases the resistance to radiation and chemotherapy, and...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer Res
Hauptverfasser: Ding, Zonghui, Roos, Alison, Kloss, Jean, Dhruv, Harshil, Peng, Sen, Pirrotte, Patrick, Eschbacher, Jennifer M., Tran, Nhan L., Loftus, Joseph C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805628/
https://ncbi.nlm.nih.gov/pubmed/29117939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0454
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