Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

Acute graft-versus-host disease (GVHD) results from the attack of host tissues by donor allogeneic T cells and is the most serious limitation of allogeneic hematopoietic cell transplantation (allo-HCT). Host antigen-presenting cells are thought to control the priming of alloreactive T cells and the...

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Main Authors: Hashimoto, Daigo, Chow, Andrew, Greter, Melanie, Saenger, Yvonne, Kwan, Wing-Hong, Leboeuf, Marylene, Ginhoux, Florent, Ochando, Jordi C., Kunisaki, Yuya, van Rooijen, Nico, Liu, Chen, Teshima, Takanori, Heeger, Peter S., Stanley, E. Richard, Frenette, Paul S., Merad, Miriam
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092347/
https://ncbi.nlm.nih.gov/pubmed/21536742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101709
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