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Upregulation of Poly (ADP-Ribose) Polymerase-1 (PARP1) in Triple-Negative Breast Cancer and Other Primary Human Tumor Types

Poly (ADP-ribose) polymerase-1 (PARP1) is a key facilitator of DNA repair and is implicated in pathways of tumorigenesis. PARP inhibitors have gained recent attention as rationally designed therapeutics for the treatment of several malignancies, particularly those associated with dysfunctional DNA r...

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Detalhes bibliográficos
Main Authors: Ossovskaya, Valeria, Koo, Ingrid Chou, Kaldjian, Eric P., Alvares, Christopher, Sherman, Barry M.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092251/
https://ncbi.nlm.nih.gov/pubmed/21779467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910383418
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