Natriuretic peptide pharmacogenetics: Membrane metallo-endopeptidase (MME): Common gene sequence variation, functional characterization and degradation

Membrane metallo-endopeptidase (MME), also known as neutral endopeptidase 24.11 (EC 3.4.24.11), is involved in the metabolism of natriuretic peptides that play a key role in modulating cardiac structure and function. Common genetic variation in MME has not been addressed by resequencing the gene usi...

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Main Authors: Pereira, Naveen L., Aksoy, Pinar, Moon, Irene, Peng, Yi, Redfield, Margaret M., Burnett, John C., Wieben, Eric D., Yee, Vivien C., Weinshilboum, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092155/
https://ncbi.nlm.nih.gov/pubmed/20692264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.07.020
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