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Structure and biosynthesis of the marine streptomycete ansamycin ansalactam A and its distinctive branched chain polyketide extender unit

Reported is the structure and biosynthesis of ansalactam A, an ansamycin class polyketide produced by an unusual modification of the polyketide pathway. This new metabolite, produced by a marine sediment-derived bacterium of the genus Streptomyces, possesses a novel spiro γ-lactam moiety and a disti...

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Detaylı Bibliyografya
Asıl Yazarlar: Wilson, Micheal C., Nam, Sang-Jip, Gulder, Tobias A. M., Kauffman, Christopher A., Jensen, Paul R., Fenical, William, Moore, Bradley S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091981/
https://ncbi.nlm.nih.gov/pubmed/21247149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja109226s
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