Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation

BACKGROUND: Identifying associations between genotypes and gene expression levels using microarrays has enabled systematic interrogation of regulatory variation underlying complex phenotypes. This approach has vast potential for functional characterization of disease states, but its prohibitive cost...

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Detalhes bibliográficos
Main Authors: Babak, Tomas, Garrett-Engele, Philip, Armour, Christopher D, Raymond, Christopher K, Keller, Mark P, Chen, Ronghua, Rohl, Carol A, Johnson, Jason M, Attie, Alan D, Fraser, Hunter B, Schadt, Eric E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091669/
https://ncbi.nlm.nih.gov/pubmed/20707912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-473
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