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Using paired-end sequences to optimise parameters for alignment of sequence reads against related genomes

BACKGROUND: The advent of cheap high through-put sequencing methods has facilitated low coverage skims of a large number of organisms. To maximise the utility of the sequences, assembly into contigs and then ordering of those contigs is required. Whilst sequences can be assembled into contigs de nov...

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Hlavní autoři: Ratnakumar, Abhirami, McWilliam, Sean, Barris, Wesley, Dalrymple, Brian P
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091654/
https://ncbi.nlm.nih.gov/pubmed/20678236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-458
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