The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids

BACKGROUND: The ubiquitin-conjugating enzyme HR6B is required for spermatogenesis in mouse. Loss of HR6B results in aberrant histone modification patterns on the trancriptionally silenced X and Y chromosomes (XY body) and on centromeric chromatin in meiotic prophase. We studied the relationship betw...

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Détails bibliographiques
Auteurs principaux: Mulugeta Achame, Eskeatnaf, Wassenaar, Evelyne, Hoogerbrugge, Jos W, Sleddens-Linkels, Esther, Ooms, Marja, Sun, Zu-Wen, van IJcken, Wilfred FJ, Grootegoed, J Anton, Baarends, Willy M
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091626/
https://ncbi.nlm.nih.gov/pubmed/20537150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-367
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