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Influence of nucleic acid base aromaticity on substrate reactivity with enzymes acting on single-stranded DNA.

Stacking between aromatic amino acids and nucleic acid bases may play an important role in the interaction of enzymes with nucleic acid substrates. In such circumstances, disruption of base aromaticity would be expected to decrease enzyme activity on the modified substrates. We have examined the req...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Weinfeld, M, Soderlind, K J, Buchko, G W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1993
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309161/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8382802/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.3.621
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