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COMIT: identification of noncoding motifs under selection in coding sequences

Coding nucleotide sequences contain myriad functions independent of their encoded protein sequences. We present the COMIT algorithm to detect functional noncoding motifs in coding regions using sequence conservation, explicitly separating nucleotide from amino acid effects. COMIT concurs with divers...

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Detalhes bibliográficos
Main Authors: Kural, Deniz, Ding, Yang, Wu, Jiantao, Korpi, Alicia M, Chuang, Jeffrey H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091326/
https://ncbi.nlm.nih.gov/pubmed/19930548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-11-r133
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