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Heme Interacts with C1q and Inhibits the Classical Complement Pathway

C1q is the recognition subunit of the first component of the classical complement pathway. It participates in clearance of immune complexes and apoptotic cells as well as in defense against pathogens. Inappropriate activation of the complement contributes to cellular and tissue damage in different p...

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Detalhes bibliográficos
Main Authors: Roumenina, Lubka T., Radanova, Maria, Atanasov, Boris P., Popov, Krastio T., Kaveri, Srinivas V., Lacroix-Desmazes, Sébastien, Frémeaux-Bacchi, Véronique, Dimitrov, Jordan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091251/
https://ncbi.nlm.nih.gov/pubmed/21454703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.206136
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