Uncoupling Charge Movement from Channel Opening in Voltage-gated Potassium Channels by Ruthenium Complexes

The Kv2.1 channel generates a delayed-rectifier current in neurons and is responsible for modulation of neuronal spike frequency and membrane repolarization in pancreatic β-cells and cardiomyocytes. As with other tetrameric voltage-activated K(+)-channels, it has been proposed that each of the four...

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Autors principals: Jara-Oseguera, Andrés, Ishida, Itzel G., Rangel-Yescas, Gisela E., Espinosa-Jalapa, Noel, Pérez-Guzmán, José A., Elías-Viñas, David, Le Lagadec, Ronan, Rosenbaum, Tamara, Islas, León D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Membrane Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091247/
https://ncbi.nlm.nih.gov/pubmed/21454671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198010
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