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Stimulus-induced S-Nitrosylation of Syntaxin 4 Impacts Insulin Granule Exocytosis
Glucose-stimulated insulin release from pancreatic islet β-cells involves increased levels of reactive oxygen and nitrogen species. Although this is normal, under pathophysiological conditions such as chronic hyperglycemia and inflammation, insulin exocytosis fails, and yet the mechanistic reason fo...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3091240/ https://ncbi.nlm.nih.gov/pubmed/21393240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.214031 |
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