Binding Strength and Dynamics of Invariant Natural Killer Cell T Cell Receptor/CD1d-Glycosphingolipid Interaction on Living Cells by Single Molecule Force Spectroscopy

Invariant natural killer T (iNKT) cells are a population of T lymphocytes that play an important role in regulating immunity to infection and tumors by recognizing endogenous and exogenous CD1d-bound lipid molecules. Using soluble iNKT T cell receptor (TCR) molecules, we applied single molecule forc...

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Detalhes bibliográficos
Main Authors: Bozna, Bianca L., Polzella, Paolo, Rankl, Christian, Zhu, Rong, Salio, Mariolina, Shepherd, Dawn, Duman, Memed, Cerundolo, Vincenzo, Hinterdorfer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091206/
https://ncbi.nlm.nih.gov/pubmed/21454514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.192674
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