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Sts-2 Is a Phosphatase That Negatively Regulates Zeta-associated Protein (ZAP)-70 and T Cell Receptor Signaling Pathways

T cell activity is controlled in large part by the T cell receptor (TCR). The TCR detects the presence of foreign pathogens and activates the T cell-mediated immune reaction. Numerous intracellular signaling pathways downstream of the TCR are involved in the process of T cell activation. Negative re...

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Hlavní autoři: San Luis, Boris, Sondgeroth, Ben, Nassar, Nicolas, Carpino, Nick
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091203/
https://ncbi.nlm.nih.gov/pubmed/21393235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177634
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