The Chondroitin Sulfate A-binding Site of the VAR2CSA Protein Involves Multiple N-terminal Domains

Malaria during pregnancy is a major health problem for African women. The disease is caused by Plasmodium falciparum malaria parasites, which accumulate in the placenta by adhering to chondroitin sulfate A (CSA). The interaction between infected erythrocytes and the placental receptor is mediated by...

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Hlavní autoři: Dahlbäck, Madeleine, Jørgensen, Lars M., Nielsen, Morten A., Clausen, Thomas M., Ditlev, Sisse B., Resende, Mafalda, Pinto, Vera V., Arnot, David E., Theander, Thor G., Salanti, Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091200/
https://ncbi.nlm.nih.gov/pubmed/21398524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191510
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