Structural and Functional Insight into How the Plasmodium falciparum VAR2CSA Protein Mediates Binding to Chondroitin Sulfate A in Placental Malaria

Malaria is a major global health problem. Pregnant women are susceptible to infection regardless of previously acquired immunity. Placental malaria is caused by parasites capable of sequestering in the placenta. This is mediated by VAR2CSA, a parasite antigen that interacts with chondroitin sulfate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Clausen, Thomas M., Christoffersen, Stig, Dahlbäck, Madeleine, Langkilde, Annette Eva, Jensen, Kamilla E., Resende, Mafalda, Agerbæk, Mette Ø., Andersen, Daniel, Berisha, Besim, Ditlev, Sisse B., Pinto, Vera V., Nielsen, Morten A., Theander, Thor G., Larsen, Sine, Salanti, Ali
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Molecular Bases of Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390611/
https://ncbi.nlm.nih.gov/pubmed/22570492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.348839
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