Folding of DNA substrate-hairpin ribozyme domains: use of deoxy 4-thiouridine as an intrinsic photolabel.

Hairpin ribozymes derived from (-)sTRSV RNA exhibit substantial cleavage activity when wobble GU base pairs are introduced in place of the AU pairs normally involved in helices I and II between substrate and ribozyme. This finding prompted us to synthesize by in vitro transcription a new hairpin rib...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Dos Santos, D V, Vianna, A L, Fourrey, J L, Favre, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1993
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.2.201
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