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Sequence specific inhibition of DNA restriction enzyme cleavage by PNA.

Plasmids containing double-stranded 10-mer PNA (peptide nucleic acid chimera) targets proximally flanked by two restriction enzyme sites were challenged with the complementary PNA or PNAs having one or two mismatches, and the effect on the restriction enzyme cleavage of the flanking sites was assaye...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Nielsen, P E, Egholm, M, Berg, R H, Buchardt, O
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1993
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8382793/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.2.197
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