DNA promoter hypermethylation of p16 and APC predicts neoplastic progression in Barrett’s esophagus

INTRODUCTION: Prediction of progression to cancer in patients with Barrett’s esophagus is difficult using current techniques. We determined whether DNA promoter hypermethylation of genes frequently methylated in esophageal adenocarcinoma (p16 and APC) could be used as predictors of progression in Ba...

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Autori principali: Wang, Jean S., Guo, Mingzhou, Montgomery, Elizabeth A., Thompson, Richard E., Cosby, Hilary, Hicks, Lisa, Wang, Shelun, Herman, James G., Canto, Marcia I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090447/
https://ncbi.nlm.nih.gov/pubmed/19584833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2009.300
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