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DNA promoter hypermethylation of p16 and APC predicts neoplastic progression in Barrett’s esophagus

INTRODUCTION: Prediction of progression to cancer in patients with Barrett’s esophagus is difficult using current techniques. We determined whether DNA promoter hypermethylation of genes frequently methylated in esophageal adenocarcinoma (p16 and APC) could be used as predictors of progression in Ba...

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Detalhes bibliográficos
Main Authors: Wang, Jean S., Guo, Mingzhou, Montgomery, Elizabeth A., Thompson, Richard E., Cosby, Hilary, Hicks, Lisa, Wang, Shelun, Herman, James G., Canto, Marcia I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090447/
https://ncbi.nlm.nih.gov/pubmed/19584833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2009.300
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