Solid self-nanoemulsifying cyclosporin A pellets prepared by fluid-bed coating: preparation, characterization and in vitro redispersibility

BACKGROUND: The objective of this study was to evaluate fluid-bed coating as a new technique to prepare a pellet-based solid self-nanoemulsifying drug delivery system (SNEDDS) using cyclosporin A as a model of a poorly water-soluble drug. METHODS: The rationale of this technique was to entrap a Liqu...

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Autori principali: Lei, Yang, Lu, Yi, Qi, Jianping, Nie, Sufang, Hu, Fuqiang, Pan, Weisan, Wu, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2011
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090276/
https://ncbi.nlm.nih.gov/pubmed/21589647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S17711
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