Solid self-nanoemulsifying cyclosporin A pellets prepared by fluid-bed coating: preparation, characterization and in vitro redispersibility

BACKGROUND: The objective of this study was to evaluate fluid-bed coating as a new technique to prepare a pellet-based solid self-nanoemulsifying drug delivery system (SNEDDS) using cyclosporin A as a model of a poorly water-soluble drug. METHODS: The rationale of this technique was to entrap a Liqu...

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Hlavní autoři: Lei, Yang, Lu, Yi, Qi, Jianping, Nie, Sufang, Hu, Fuqiang, Pan, Weisan, Wu, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2011
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090276/
https://ncbi.nlm.nih.gov/pubmed/21589647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S17711
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