Loading...

Coupled 5′ nucleotide recognition and processivity in Xrn1-mediated mRNA decay

Messenger RNA decay plays a central role in the regulation and surveillance of eukaryotic gene expression. The conserved multi-domain exoribonuclease Xrn1 targets cytoplasmic RNA substrates marked by a 5′ monophosphate for processive 5′-to-3′ degradation by an unknown mechanism. Here we report the c...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Jinek, Martin, Coyle, Scott M., Doudna, Jennifer A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090138/
https://ncbi.nlm.nih.gov/pubmed/21362555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.02.004
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!