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Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links
The present review highlights an association between autism, Alzheimer disease (AD), and fragile X syndrome (FXS). We propose a conceptual framework involving the amyloid-β peptide (Aβ), Aβ precursor protein (APP), and fragile X mental retardation protein (FMRP) based on experimental evidence. The a...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Lippincott Williams & Wilkins
2011
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090060/ https://ncbi.nlm.nih.gov/pubmed/21482951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182166dc7 |
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