Structural analysis of 5′-mRNA–cap interactions with the human AGO2 MID domain

In RNA silencing, microRNA (miRNA)-mediated translational repression occurs through mechanisms that do not invoke messenger-RNA (mRNA) target cleavage by Argonaute proteins. The nature of these mechanisms is unclear, but several recent studies have proposed that a direct interaction between the mRNA...

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Detalhes bibliográficos
Main Authors: Frank, Filipp, Fabian, Marc R, Stepinski, Janusz, Jemielity, Jacek, Darzynkiewicz, Edward, Sonenberg, Nahum, Nagar, Bhushan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090017/
https://ncbi.nlm.nih.gov/pubmed/21475248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.48
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