The Novel Nicotinic Receptor Antagonist, N,N′-Dodecane-1,12-diyl-bis-3-picolinium Dibromide (bPiDDB), Inhibits Nicotine-evoked [(3)H]Norepinephrine Overflow from Rat Hippocampal Slices

Smoking is a significant health concern and strongly correlated with clinical depression. Depression is associated with decreased extracellular NE concentrations in brain. Smokers may be self-medicating and alleviating their depression through nicotine stimulated norepinephrine (NE) release. Several...

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Main Authors: Smith, Andrew M., Dhawan, Gurpreet K., Zhang, Zhenfa, Siripurapu, Kiran B., Crooks, Peter A., Dwoskin, Linda P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090002/
https://ncbi.nlm.nih.gov/pubmed/19631612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.07.010
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