HIV-1 Envelope Induces Memory B Cell Responses That Correlate with Plasma Antibody Levels after Envelope gp120 Protein Vaccination or HIV-1 Infection

Successful vaccines (i.e., tetanus and diphtheria) can induce long-lived Ab levels that are maintained by bone marrow plasma cells and plasma Ab levels do not correlate with numbers of blood memory B cells. Destruction of CD4(+) T cells early in HIV-1 acute infection may result in insufficient induc...

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Bibliographische Detailangaben
Hauptverfasser: Bonsignori, Mattia, Moody, M. Anthony, Parks, Robert J., Holl, T. Matt, Kelsoe, Garnett, Hicks, Charles B., Vandergrift, Nathan, Tomaras, Georgia D., Haynes, Barton F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089979/
https://ncbi.nlm.nih.gov/pubmed/19625640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901068
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