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The role of tropomyosin isoforms and phosphorylation in force generation in thin-filament reconstituted bovine cardiac muscle fibres

The thin filament extraction and reconstitution protocol was used to investigate the functional roles of tropomyosin (Tm) isoforms and phosphorylation in bovine myocardium. The thin filament was extracted by gelsolin, reconstituted with G-actin, and further reconstituted with cardiac troponin togeth...

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Main Authors: Lu, Xiaoying, Heeley, David H., Smillie, Lawrence B., Kawai, Masataka
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089900/
https://ncbi.nlm.nih.gov/pubmed/20559861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-010-9213-x
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