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Role of the N-terminal negative charges of actin in force generation and cross-bridge kinetics in reconstituted bovine cardiac muscle fibres

Mutant yeast actins were used to determine the role of actin's N-terminal negative charges in force generation. The thin filament was selectively removed from bovine cardiac skinned muscle fibres by gelsolin, and the actin filament was reconstituted from purified G-actin. In this reconstitution...

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Detalhes bibliográficos
Main Authors: Lu, Xiaoying, Bryant, Mary K, Bryan, Keith E, Rubenstein, Peter A, Kawai, Masataka
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456038/
https://ncbi.nlm.nih.gov/pubmed/15649975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.078055
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