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ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression

Dynamic regulation of diverse nuclear processes is intimately linked to covalent modifications of chromatin1,2. Much attention has focused on methylation at lysine 4 of histone H3 (H3K4), owing to its association with euchromatic genomic regions3,4. H3K4 can be mono-, di- or tri-methylated. Trimethy...

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Autores principales: Shi, Xiaobing, Hong, Tao, Walter, Kay L., Ewalt, Mark, Michishita, Eriko, Hung, Tiffany, Carney, Dylan, Peña, Pedro, Lan, Fei, Kaadige, Mohan R., Lacoste, Nicolas, Cayrou, Christelle, Davrazou, Foteini, Saha, Anjanabha, Cairns, Bradley R., Ayer, Donald E., Kutateladze, Tatiana G., Shi, Yang, Côté, Jacques, Chua, Katrin F., Gozani, Or
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089773/
https://ncbi.nlm.nih.gov/pubmed/16728974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04835
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