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DNA damage response regulates cell differentiation
When faced with DNA double strand breaks (DSBs), vertebrate cells activate DNA damage response (DDR) programs that preserve genome integrity and suppress malignant transformation. Three established outcomes of the DDR include transient cell cycle arrest coupled with DNA repair, apoptosis, or senesce...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3089693/ https://ncbi.nlm.nih.gov/pubmed/21354798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2011.01.004 |
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