Genotype-Environment Interactions in Microsatellite Stable/Microsatellite Instability-Low Colorectal Cancer: Results from a Genome-Wide Association Study

BACKGROUND: Genome-wide association studies (GWAS) have led to the identification of a number of common susceptibility loci for colorectal cancer (CRC); however, none of these GWAS have considered gene-environment (GxE) interactions. Therefore, it is unclear whether current hits are modified by envi...

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Hauptverfasser: Figueiredo, Jane C., Lewinger, Juan Pablo, Song, Chi, Campbell, Peter T., Conti, David V., Edlund, Christopher K., Duggan, Dave J., Rangrej, Jagadish, Lemire, Mathieu, Hudson, Thomas, Zanke, Brent, Cotterchio, Michelle, Gallinger, Steven, Jenkins, Mark, Hopper, John, Haile, Robert, Newcomb, Polly, Potter, John, Baron, John A., Marchand, Loic Le, Casey, Graham
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089660/
https://ncbi.nlm.nih.gov/pubmed/21357381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-0675
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