Quality Assessment and Correlation of Microsatellite Instability and Immunohistochemical Markers among Population- and Clinic-Based Colorectal Tumors: Results from the Colon Cancer Family Registry

The detection of defective mismatch repair (MMR), as assessed by the presence of tumor microsatellite instability (MSI) and/or loss of MMR protein expression by IHC, has been useful for risk assessment, prognosis, and prediction of treatment in patients with colorectal cancer. We analyzed tumors for...

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Bibliographic Details
Main Authors: Cicek, Mine S., Lindor, Noralane M., Gallinger, Steven, Bapat, Bharati, Hopper, John L., Jenkins, Mark A., Young, Joanne, Buchanan, Daniel, Walsh, Michael D., Le Marchand, Loic, Burnett, Terrilea, Newcomb, Polly A., Grady, William M., Haile, Robert W., Casey, Graham, Plummer, Sarah J., Krumroy, Lisa A., Baron, John A., Thibodeau, Stephen N.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2011
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077724/
https://ncbi.nlm.nih.gov/pubmed/21497289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2010.12.004
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