Two Distinct Integrin-Mediated Mechanisms Contribute to Apical Lumen Formation in Epithelial Cells

BACKGROUND: Formation of apical compartments underlies the morphogenesis of most epithelial organs during development. The extracellular matrix (ECM), particularly the basement membrane (BM), plays an important role in orienting the apico-basal polarity and thereby the positioning of apical lumens....

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Main Authors: Myllymäki, Satu Marja, Teräväinen, Terhi Piritta, Manninen, Aki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089628/
https://ncbi.nlm.nih.gov/pubmed/21573123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019453
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