The X Protein of Hepatitis B Virus Inhibits Apoptosis in Hepatoma Cells through Enhancing the Methionine Adenosyltransferase 2A Gene Expression and Reducing S-Adenosylmethionine Production

The X protein (HBx) of hepatitis B virus (HBV) is involved in the development of hepatocellular carcinoma (HCC), and methionine adenosyltransferase 2A (MAT2A) promotes the growth of liver cancer cells through altering S-adenosylmethionine homeostasis. Thus, we speculated that a link between HBx and...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Quanyan, Chen, Jiwei, Liu, Li, Zhang, Jun, Wang, Dongfeng, Ma, Lu, He, Yueming, Liu, Yingle, Liu, Zhisu, Wu, Jianguo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089560/
https://ncbi.nlm.nih.gov/pubmed/21247894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.167783
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