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Calcium-induced Folding of Intrinsically Disordered Repeat-in-Toxin (RTX) Motifs via Changes of Protein Charges and Oligomerization States

Ligand-induced disorder-to-order transition plays a key role in the biological functions of many proteins that contain intrinsically disordered regions. This trait is exhibited by so-called RTX (repeat-in-toxin) motifs found in many virulence factors secreted by numerous Gram-negative pathogenic bac...

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Autori principali: Sotomayor-Pérez, Ana Cristina, Ladant, Daniel, Chenal, Alexandre
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089544/
https://ncbi.nlm.nih.gov/pubmed/21454565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210393
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