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Nucleoside Triphosphate Pool Asymmetry in Mammalian Mitochondria
Our laboratory has reported that deoxyribonucleoside triphosphate (dNTP) pools in rat tissue mitochondria are highly asymmetric, with dGTP predominating, and that the imbalance probably contributes toward the high spontaneous mutation rate of the mitochondrial genome. Ferraro et al. (Ferraro, P., Ni...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3089543/ https://ncbi.nlm.nih.gov/pubmed/21454602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236968 |
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