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Nucleoside Triphosphate Pool Asymmetry in Mammalian Mitochondria

Our laboratory has reported that deoxyribonucleoside triphosphate (dNTP) pools in rat tissue mitochondria are highly asymmetric, with dGTP predominating, and that the imbalance probably contributes toward the high spontaneous mutation rate of the mitochondrial genome. Ferraro et al. (Ferraro, P., Ni...

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Detalles Bibliográficos
Main Authors: Wheeler, Linda J., Mathews, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089543/
https://ncbi.nlm.nih.gov/pubmed/21454602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236968
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