AMP-activated Protein Kinase (AMPK) Activation and Glycogen Synthase Kinase-3β (GSK-3β) Inhibition Induce Ca(2+)-independent Deposition of Tight Junction Components at the Plasma Membrane

Extracellular Ca(2+) is essential for the development of stable epithelial tight junctions. We find that in the absence of extracellular Ca(2+), AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase (GSK)-3β inhibition independently induce the localization of epithelial tight j...

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Detalhes bibliográficos
Main Authors: Zhang, Li, Jouret, Francois, Rinehart, Jesse, Sfakianos, Jeff, Mellman, Ira, Lifton, Richard P., Young, Lawrence H., Caplan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089531/
https://ncbi.nlm.nih.gov/pubmed/21383016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.186932
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