Angiogenic Functions of Voltage-gated Na(+) Channels in Human Endothelial Cells: MODULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) SIGNALING

Voltage-gated sodium channel (VGSC) activity has previously been reported in endothelial cells (ECs). However, the exact isoforms of VGSCs present, their mode(s) of action, and potential role(s) in angiogenesis have not been investigated. The main aims of this study were to determine the role of VGS...

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Detalhes bibliográficos
Main Authors: Andrikopoulos, Petros, Fraser, Scott P., Patterson, Lisa, Ahmad, Zahida, Burcu, Hakan, Ottaviani, Diego, Diss, James K. J., Box, Carol, Eccles, Suzanne A., Djamgoz, Mustafa B. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089528/
https://ncbi.nlm.nih.gov/pubmed/21385874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.187559
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