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Endothelial Angiogenesis and Barrier Function in Response to Thrombin Require Ca(2+) Influx through the Na(+)/Ca(2+) Exchanger
Thrombin acts on the endothelium by activating protease-activated receptors (PARs). The endothelial thrombin-PAR system becomes deregulated during pathological conditions resulting in loss of barrier function and a pro-inflammatory and pro-angiogenic endothelial phenotype. We reported recently that...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513102/ https://ncbi.nlm.nih.gov/pubmed/25979335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628156 |
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