Developmental Control of Apoptosis by the Immunophilin Aryl Hydrocarbon Receptor-interacting Protein (AIP) Involves Mitochondrial Import of the Survivin Protein

Survivin is a multifunctional protein with essential roles in cell division and inhibition of apoptosis, but the molecular underpinnings of its cytoprotective properties are poorly understood. Here we show that homozygous deletion of the aryl hydrocarbon receptor-interacting protein (AIP), a survivi...

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Detalles Bibliográficos
Main Authors: Kang, Byoung Heon, Xia, Fang, Pop, Ramona, Dohi, Takehiko, Socolovsky, Merav, Altieri, Dario C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089518/
https://ncbi.nlm.nih.gov/pubmed/21454573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210120
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