miRNA-205 Suppresses Melanoma Cell Proliferation and Induces Senescence via Regulation of E2F1 Protein

MicroRNAs (miRNAs) regulate gene expression by repressing translation or directing sequence-specific degradation of complementary mRNA. Here, we report that expression of miR-205 is significantly suppressed in melanoma specimens when compared with nevi and is correlated inversely with melanoma progr...

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Bibliographic Details
Main Authors: Dar, Altaf A., Majid, Shahana, de Semir, David, Nosrati, Mehdi, Bezrookove, Vladimir, Kashani-Sabet, Mohammed
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Molecular Bases of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089503/
https://ncbi.nlm.nih.gov/pubmed/21454583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.227611
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